HemostOD Laboratory - Engineering Platelets

We engineer
and manufacture
platelets.

Inspired by platelet biology to save lives

HemostOD's technology platform unlocks the power of platelets in:

Thrombocytopenia

lead program 1

Developing universal* platelets for treatment in patients with, or at risk of, HLA immune-refractoriness.

Tissue-targeted cargo delivery

lead program 2

Using our unique CAR-PLT* technology for shielded delivery of miRNA/siRNA or proteins to specific target tissues.

Regenerative medicine

Using engineered platelets in wound healing, anti-inflammatory and immunomodulating applications.

Culture of therapeutic stem cells

Using platelet lysate produced from our universal platelets to boost cell proliferation.

* engineered to be HLA-low

HemostOD: a swiss-based preclinical company

Founded in 2020, HemostOD is a biotech company based at the EPFL Innovation Park in Lausanne, Switzerland.

We are a preclinical stage company developing applications based on our proprietary platform to engineer and manufacture universal platelets.

A unique & scalable
platelet manufacturing
platform

Inspired by the physiological generation of platelets in the bone marrow, HemostOD has developed an innovative solution to manufacture engineered platelets, thereby providing a practically unlimited source of universal platelets.

Our unique process integrates molecular & cell biology techniques to build a stable megakaryocitic cell line (steps 1, 2 & 3), followed by the use of advanced microfluidic technologies in a bioreactor to fragment megakaryocytes into platelets (step 4). This robust and rapid process enables the generation of large quantities of homogeneous and high-quality platelets in a few hours.

Our IP-protected platform includes:

1

Immortalization of hematopoietic progenitors (stem) cells from a single donor.

2

Engineering of cells to introduce custom features, modifying the platelet surface and/or content for controlled release.

3

Differentiation into a practically unlimited source of megakaryocytes, the platelet progenitor cells.

4

Ex-vivo generation of platelets in a robust, fast and scalable manufacturing process.

HemostOD Technology Process - 4 Steps Visual Diagram
HemostOD Partnering Opportunities - Scientific Research

Partnering opportunities

We are open to collaborations and welcome enquiries about partnership opportunities for applications in all our target areas:

  • Thrombocytopenia
  • Tissue-targeted cargo delivery technology (CAR-PLT*)
  • Regenerative medicine
  • Culture of therapeutic stem cells (platelet lysate)
  • and beyond.

For enquiries, please contact:

contact@hemostod.com

A multidisciplinary team

Faouzi Khechana - CEO

Faouzi Khechana

CEO

Laurent Massuyeau - Executive Chairman

Laurent Massuyeau

Executive Chairman

Nicoletta Sorvillo, PhD - CSO

Nicoletta Sorvillo, PhD

CSO

Elodie Dahan, PhD - CTO

Elodie Dahan, PhD

CTO

Chris Wiltshire - CBO

Chris Wiltshire

CBO

Our partners

Swiss Biotech Center
Swiss Confederation
FIT - Fondation pour l'innovation Technologique
Venture Kick
Centre hospitalier universitaire vaudois (CHUV)
EPFL
Canton de Vaud
UNIL - Université de Lausanne
EIT Health
Lichtsteiner Foundation

Join us

We do not have any open positions at the moment, but we are always happy to hear from interested talents. Please reach out to us by email at the address below.